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Maturation Phenomenon in Cerebral Ischemia IV

by N.G. . Bazan
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
Genre: Medical
Pages: 284 pages
ISBN 13: 3642594468
ISBN 10: 9783642594465
Format: PDF, ePUB, MOBI, Audiobooks, Kindle

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Synopsis : Maturation Phenomenon in Cerebral Ischemia IV written by N.G. . Bazan, published by Springer Science & Business Media which was released on 2012-12-06. Download Maturation Phenomenon in Cerebral Ischemia IV Books now! Available in PDF, EPUB, Mobi Format. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. -- The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. It outlines the present status of investigations and provides further stimulation for research in this field.

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Maturation Phenomenon in Cerebral Ischemia IV
Language: en
Pages: 284
Authors: N.G. . Bazan, U. Ito, V.L. Marcheselli, T. Kuroiwa, I. Klatzo
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. It outlines the present status of investigations and provides further stimulation for research in this field.
Maturation Phenomenon in Cerebral Ischemia III
Language: en
Pages: 343
Authors: Umeo Ito, Cesare Fieschi, Francesco Orzi, Toshihiko Kuroiwa, Igor Klatzo
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

The Maturation Phenomenon, described by Ito et al. in 1975 [3) on the basis of his to logical observations in the hippocampus as well as other portions of the cerebral hemisphere, refers to the hours or days of delay in the development of pathological changes in various parameters of ischemic injury following the restoration of blood flow to the ischemic brain. There is a direct relationship between the intensity of ischemic insult and the speed and rate of maturation of ischemic injury, a lesser intensity being associated with slower and less severe development of the lesions. The delayed neuronal death of CAl pyramidal cells of the hippocampus [8) is a classic example. In the cerebral cortex, with increasing intensity of the ischemic insult, the maturation phenomenon of ischemic injuries intensifies, seamlessly, from less exten sive to more extensive disseminated selective neuronal necrosis (DSNN), and then further to cerebral infarction upon reaching a critical threshold [1,2,4,6,7). We also have found that following ischemic insults just under the threshold level required to induce infarction, only disseminated selective neuronal necrosis (DSNN) progresses, while following ischemic insults at the threshold level, initially only DSNN develops, followed by the evolution of a gradually enlarging infarcted focus [5, 7). The reporting of this phenomenon boosted research in the field, as it became evi dent that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention.
Maturation Phenomenon in Cerebral Ischemia V
Language: en
Pages: 362
Authors: A.M. Buchan, U. Ito, F. Colbourne, T. Kuroiwa, I. Klatzo
Categories: Medical
Type: BOOK - Published: 2003-12-08 - Publisher: Springer

The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the Fifth International Workshop on Maturation Phenomenon in Cerebral Ischemia, held in Banff, Alberta, Canada, in April/May 2002. It outlines the present status of investigations and provides further stimulation for research in this field.
Maturation Phenomenon in Cerebral Ischemia
Language: en
Pages: 208
Authors: U. Ito, T. Kirino, T. Kuroiwa, I. Klatzo
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

It has been well recognized that following an ischemic insult many nerve cells of the brain are not killed outright, but may suffer a "delayed neuronal death" or even recover. This led to the concept of "maturation phenomenon" with its main implication that the maturation of ischemic lesions may provide a "window of opportunity" i.e. a period of time when the injury to neuronal elements is still reversible, and during which an application of proper therapeutic measures might be successful. The symposium on Maturation Phenomenon in Cerebral Ischemia was the first international meeting focussed primarily on this subject and the resulting publication contains presentations and discussionsby prominent researchers engaged in this field. This book should stimulate further research on potential of brain tissue for recovery, and particularly with regard to a functional recovery of neurons suffering from chronic ischemic injury.
Maturation Phenomenon in Cerebral Ischemia II
Language: en
Pages: 225
Authors: Umeo Ito, Takaaki Kirino, Toshihiko Kuroiwa, Igor Klatzo
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Many nerve cells of the brain which are not killed outright may suffer delayed death or recovery after ischemic insult. This fact has led to the concept of "maturation phenomenon" of neuronal injuries. Since the 1st International Symposium on Maturation Phenomenon in 1990, new developments, particularly in molecular biology, have been rapidly bringing new information about molecular nature and mechanisms of cell death. This book contains the presentations of the 2nd International Symposium held in Tokyo in April 1996. The latest developments in maturation phenomenon and the present status of investigation are described and further stimulation of research in this field is provided.
Maturation Phenomenon in Cerebral Ischemia
Language: en
Pages:
Authors: Umeo Ito, Takaaki Kirino, Toshihiko Kuroiwa, Igor Klatzo
Categories: Medical
Type: BOOK - Published: 1997 - Publisher:

Books about Maturation Phenomenon in Cerebral Ischemia
Maturation Phenomenon in Cerebral Ischemia V
Language: en
Pages: 362
Authors: Umeo Ito, Takaaki Kirino, Toshihiko Kuroiwa, Igor Klatzo
Categories: Apoptosis
Type: BOOK - Published: 2004 - Publisher:

Books about Maturation Phenomenon in Cerebral Ischemia V
Maturation Phenomenon in Cerebral Ischemia
Language: en
Pages:
Authors: Umeo Ito, Takaaki Kirino, Toshihiko Kuroiwa, Igor Klatzo
Categories: Apoptosis
Type: BOOK - Published: - Publisher:

Books about Maturation Phenomenon in Cerebral Ischemia
Maturation Phenomenon in Cerebral Ischemia
Language: en
Pages: 208
Authors: Umeo Ito
Categories: Medical
Type: BOOK - Published: 1992 - Publisher: Springer Verlag

Books about Maturation Phenomenon in Cerebral Ischemia
Maturation Phenomenon in Cerebral Ischemia IV.
Language: en
Pages: 7
Authors: Umeo Ito
Categories: Medical
Type: BOOK - Published: 2001 - Publisher:

Young animals were previously shown to be more resistant to ischemia than were adult animals. This difference was attributed to maturation/function of gonads and/or neurons. This study evaluated the existence of age-related changes in transcriptional expression of HSC70, HSP72, and c-fos mRNA intransient global ischemia, and their possible relationship to neuronal cell survival in CA1 hippocampus. The results indicated that ischemic response in young animals compared with that in adult animals showed: (1) more rapid and /or prolonged expression of HSC70, HSP72, and c-fos mRNAs; (2) a marked induction of HSP72 protein; and (3) enhanced pyramidal cell survival. The observed endogenous 'tolerance' of CA1 neurons in young gerbils to ischemia/reperfusion injury may be related to the expression of HSC70, HSP72 and c-fos.
Brain Edema XII
Language: en
Pages: 612
Authors: T. Kuroiwa, A. Baethmann, Z. Czernicki, J.T. Hoff, U. Ito, Y. Katayama, A. Marmarou, D. Mendelow, H.-J. Reulen
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Brain edema is a simple phenomenon – an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.
Brain Edema X
Language: en
Pages: 302
Authors: H.E. James, L.F. Marshall, H.J. Reulen, A. Baethmann, A. Marmarou, U. Ito, J.T. Hoff, T. Kuroiwa, Z. Czernicki
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

This volume is a compilation of papers presented at the Tenth International Symposium on Brain Edema held on October 20-23, 1996, in San Diego, California. This follows the sequence of meetings that was initiated 31 years ago in the First International Symposium held in Vienna. Subsequent symposiums were held in Mainz, Montreal, Berlin, Groningen, Tokyo, Baltimore, Bern, and Tokyo CY okohama). A considerable number of papers was chosen from over 100 papers that were received. The organizers wish to thank the Advisory Committee for the excellent work done in selection of the papers. We also wish to thank all the persons who contributed to the success of the Tenth International Symposium, especially the staff who worked behind the scenes. These papers were reviewed, edited, approved or disapproved by the Editorial Board. Those manuscripts that were felt not pertinent to this publication were not accepted by the Editorial Board. Therefore, the excellent quality of those that are in the book are a reflection of the authors' dedication and work and that of those of the Editorial Board in their review process. For the reader's convenience, the papers are structured according to the various disease processes which are associated with the primary topic: hypertension, hydrocephalus, infection, ischemia, tumor, etc. We do hope that the reader will enjoy the articles and that they will provide an impetus and insight for future work.